Presents the

Olin Seminar Series:

“From Sequence to

Consequence”

 

featuring

 

Professor Dagmar Ringe,

Departments of Biochemistry and Chemistry and

Rosenstiel Basic Medical

Sciences Research Center, Brandeis University

 

 

Friday, October 31st, 2003

2 to 3 PM

(refreshments at 1:30 PM)

Olin Center Auditorium,

Olin College

 

 

 

 

 

 

 

 

 

 

ABSTRACT:

 

Genomics, the study of the properties of genes and gene products on a whole-organism scale, is revolutionizing all aspects of biology.  The ultimate goals are the determinations of the functions of all gene products of an organism within the context of the organism, at all levels from the molecular to the organism as a whole.  Among the fields that has the potential to aid in that process is the field of structural biology.  Structural genomics has as its stated goals the filling-in of the catalog of known protein folds and the assignment of function to gene products whose functions are not known by structural similarity to proteins of known function.  How realistic are these goals?  Can these goals be achieved by computational means?  How robust are the predictive methods that take sequence to function?